Showing posts with label Microorganisms. Show all posts
Showing posts with label Microorganisms. Show all posts

Friday, August 27, 2010

Streptococcus pyogenes-a Gram-positive

Streptococcus pyogenes (group A streptococcus) is a Gram-positive, immobile, nonsporeforming coccus occurring in the network or in pairs of cells. Individual cells are round to ovoid cocci, 0.6 to 1.0 microns in diameter (Fig. 1). Distribution of streptococci in a plane, and therefore occur in pairs, or (particularly in tests of fluid or material) in the network of variable length. The metabolism of S. pyogenes is fermentative, catalase-negative anaerobic organism aérotolérantes anaerobic (facultative anaerobes) and requires enriched medium containing blood to grow. Streptococcus group typically consists of a capsule of hyaluronic acid and beta show hemolysis (clear) on blood agar.



Group A streptococci are human parasites and Streptococcus pyogenes is a human pathogen most frequently. It is estimated that between 5-15% of normal individuals harbor Streptococcus pyogenes, mainly in the respiratory tract, without signs of disease. During the host defense is compromised, or when the body is able to exert its virulence, or when it is placed on the sensitive tissues or hosts, acute infection.

During the last century, infections by S. pyogenes claimed many lives especially since the body is the most important cause of puerperal fever (sepsis after childbirth). Scarlet fever once a serious complication of streptococcal infection, but now, thanks to antibiotic treatment, it is a little more strep throat accompanied by a rash. Similarly, Rose (a type of cellulitis accompanied by fever and systemic toxicity) is less common today. However, there has been a recent increase in the variety, severity and consequences of infection with Streptococcus pyogenes and the resurgence of severe invasive infections, prompting descriptions of skin bacteria "eat" in the media. A full explanation of inheritance and rebirth is not known. Today, the pathogen of major concern because of sporadic cases of rapidly progressive disease and because of the low risk of serious consequences of untreated infections in. These diseases are a major health problem worldwide, and effort is directed to clarify the risks and consequences and the identification of strains and rheumatogenic nephritogenic streptococci.

Acute Streptococcus pyogenes infections may present as pharyngitis (sore throat), scarlet fever (rash), impetigo (infection of the superficial layers of the skin) or cellulitis (infection of the deeper layers of the skin). Invasive, toxic, can cause infection of necrotizing fasciitis, myositis and streptococcal toxic shock syndrome. Patients may also develop the immune system after streptococcal sequelae such as rheumatic fever and acute glomerulonephritis, following acute infections caused by Streptococcus pyogenes.

Streptococcus pyogenes produces a wide range of virulence factors and a wide range of diseases. virulence factors of group A streptococci include: (1) M-protein associated with cellular protein (protein F) and lipoteichoic acid to observe, (2) hyaluronic acid capsule immunological disguise and inhibits phagocytosis, M protein inhibits phagocytosis (3) invasins such as streptokinase, streptodornase (DNase B), hyaluronidase and streptolysin, (4) exotoxins, such as auto-ignition (erythrogenic) toxin which causes a rash of scarlet fever and systemic syndrome toxic shock.

Modes of Transmission of Cholera

Definition
Cholera is an infectious disease caused by bacterial toxin that affects the water absorption in the small intestine.
                                                                   figure via aeschines-afroza

In severe cases, produces a severe diarrhea in a few days. dangerous aspect of cholera is a significant loss of fluids, which can occur in a short period of time. This is especially dangerous in children in developing countries. If untreated, the loss of fluids can cause death within 24 hours of onset. On the other hand, the treatment is simple: replace the liquid with an appropriate combination of sugar and salt - the water itself is not sufficiently absorbed. But the worst cases require hospitalization, where the fluids can be administered directly into the blood infusion.

Damn this is not a tropical disease, but it is related to hygiene standards and quality of drinking water. It was a well in London in 1850-1860, which was the source of the cholera epidemic several separate. John Snow, is considered the father of public health service by its simple but brilliant move to pump water from Broad Street! Improved sanitation and hygiene remains the mainstay of the fight against cholera in those countries in which it occurs.

What are the causes of cholera?
Cholera is caused by a particular bacterium, Vibrio cholerae. With the right amount of bacteria passed into the stomach of food, they accumulate and begin to produce toxic substances (toxins). This toxin, which causes symptoms of the disease. Cholera toxin has an unpleasant effect on the ability of cells of the gastrointestinal tract, so that the victim is not just diarrhea, but also begins to lose large amounts of fluids. It is the loss of fluids, which can be severe.

Damn, how is it transmitted?
The bacteria are excreted in the stool, and if you come into contact with drinking water, bacteria can infect humans. The bacteria can also spread to food, if people do not wash their hands after using the toilet. Food prepared at the funeral of victims of cholera is a common source of secondary spread in Africa!

Diseases can be applied to all fish and shellfish from polluted waters. Shellfish filter large quantities of water and concentrate the bacteria. The cholera outbreak in Peru in 1998 were contaminated by algae, and it seems to be an effective way to disseminate the coast cholera.

Direct infection by contact with another person by their faeces or vomiting may occur, but this rarely happens. A number of bacteria is necessary for persons with normal gastric acid ill (stomach acid can kill a small number of bacteria). Yes, the bacteria need to multiply in the possibility of water or food before actually poses a threat.

Where the hell is happening?
Cholera is widespread in Asia and Africa, where epidemics occur at regular intervals. Unfortunately, the "El Tor bacteria shit" come to the part of Peru in the 1990s. From there it spread rapidly in the rest of South America.

Densely populated regions of poor sanitation and unsatisfactory food hygiene are particularly vulnerable to epidemics.

What are the symptoms?
The incubation period from infection to disease occurs, is usually less than two days, although it may be as long as five days.

The infection is often mild diarrhea common disease, and may even develop without any symptoms. But the body is still capable of transmitting the disease.

usually starts with a shit short time with abdominal pain without nausea. It may also be a slight fever. Then began vomiting and diarrhea and may take several hours.

It is followed by copious, watery diarrhea, pallor and flaky like rice water. The loss of fluids can be as high as 1 liter per hour.

Danger signals
If the loss of fluids and do not receive more than 5 to 10 liters, can be fatal.

Prolonged dehydration can cause skin floppy muscle cramps and a hoarse voice. There is also an impact on the level of consciousness, which can manifest itself in lethargy and confusion.

Electrolyte (salt) balance may be disrupted. Especially in children, it can cause seizures or cardiac arrest.

Perspective
Mild cases of cholera usually recover on their own.

Classic cholera has a high mortality rate if left untreated. In developing countries, mortality among people in the hospital without treatment is 60 percent.

If the disease is treated early and properly, the mortality rate is less than 1 percent, and the patient recovers completely.

How can I avoid infection?
  • Only drink boiled water or water that have been sterilized or treated in any way. The hot coffee and tea, sodas and other bottled beverages are generally safe to drink unpolluted.
  • Boil unpasteurized milk before drinking it.
  • Avoid ice in drinks, unless you can be sure they were made of "pure water"! Ice questionable sources may be contaminated.
  • Food should be well prepared and served hot. If it does not sit at room temperature for several hours of other bacteria such as Escherichia coli, can develop.
  • Avoid raw fish and shellfish.
  • Avoid raw fruits and vegetables unless you peel yourself.
  • Beware of food from street stalls. If you have to eat these foods, think carefully about its preparation. Make sure it contains nothing that has not been sufficiently prepared.

This review not only protects against cholera, but also against a number of bacteria that can cause diarrhea unpleasant. Some bacteria, however, produce toxins, which are not destroyed by cooking. Therefore, proper food storage is also important.

Vaccination against cholera is now possible with the oral vaccine Dukoral. But the vaccine does not protect 100 percent against the disease, and those who received the vaccine will still need to comply with the above measures to avoid disease. The vaccine is most suitable for tourists and business travelers in situations where the biggest risk is the shit (eg refugee camps).

If you think you catch hell for a trip
If you think you catch the shit, you should immediately contact your doctor. But do not despair if you're away from the hospital or doctor.

The most important thing you can do yourself, in all cases of violent diarrhea is to drink plenty of fluids with salt and sugar (alternatives with flat Coca-Cola), even if vomiting between both. These powders with salt, sugar and baking in the appropriate proportions of the mixture, which can be dissolved in water and taken as Dioralyte and Electrolade.

You can also call the following liquid ingredients. The liquid should be about as salty as tears.
  • 1 liter of boiled water.
  • Level 8 or 4 teaspoons of sugar (white, brown or honey).
  • 1 / 2 teaspoon salt.
  • lemon juice or orange juice.
How is the disease diagnosed?
Cause of many diseases, diarrhea. But if it is violence with stools, the doctor treated immediately. For diagnosis, the stool should be examined to detect the cholera bacterium.

How to treat cholera?
In severe cases, the disease must be treated in hospital. The first and most fundamental measure is to replace lost fluids. If speed is important, the liquid can be applied directly into the blood infusion. During the epidemic, 90 percent of those patients would be nice if they drink large quantities of water. The disease can be shortened and the shedding stopped earlier, administration of antibiotics

Types of Microorganisms

There are five types of micro-organisms: bacteria, viruses, protozoa, fungi and worms (worms).

Bacteria
The most common organisms on Earth, bacteria live almost everywhere in soil and water, plants and animals. Is this the shape of balls, rods or spirals, bacteria consists of a single cell. Unlike animal and plant cells, bacterial cells lack nuclei, but can perform all functions necessary for life. Most bacteria are parasites, but a few manufacturing their own food. Some of these parasites are very useful - they contribute to many bodily functions including digestion and aid in other processes such as soil degradation and changes in milk for cheese. The results of the disease, however, when bacteria multiply rapidly (each cell simply divides into two identical cells) and damage or kill human tissue, such as pneumonia and tuberculosis. Diseases can also produce toxins that kill or damage the tissues of humans, as in food poisoning or cholera. Sometimes, the bacteria in the body, help for a while, and then something in the body or the bacteria changes, causing destruction of the host.

Bacteria present in the image from top right: E. coli 0157: H7 (food poisoning cases), pyrogenes Strepococcus (causes strep throat), Mycobacterium tuberculosis (TB cases)


Virus
Certainly the smallest bacteria, viruses can occur in spirals, figure 20 or face a form more complicated. They consist mainly of genetic material - DNA or RNA. Cells, but they are not and can not exercise the functions of life by their own means. Living inside the cells of other species, viruses use host cell growth and the creation of new viral particles. How did they acquire genetic material for breeding, often the death of host cells. Find all groups of living things, bacteria and fungi to plants and animals, hundreds of known viruses can cause various infections, chickenpox, measles, influenza, colds, polio and AIDS. Viruses can not move by itself and must be done to cells by air currents and then by body fluids in the cells. Some viruses may lay dormant for years and starts, as in the case of AIDS. Most diseases from other species, for example: smallpox dogs or cattle, hemorrhagic fever in rodents and monkeys, tuberculosis from cattle and birds, horses with colds and AIDS African monkeys.

Viruses in the right image above: Adenovirus causes colds (), influenza causes (flu), and Hepadnavirus (causes hepatitis B)


Protozoa
Protozoa consist of a single cell that contains the nucleus. Cell also contains structures that carry out specific processes needed for life functions. complex and diverse group, the scope of protozoa in many shapes and sizes. They are parasites that must live in different organisms, or living freely in moist habitats. The similarity of the internal structure of protozoa and human cells, it is difficult to treat infections caused by protozoa. Drugs that may destroy the protozoan may destroy human cells. protozoal infections are amoebic dysentery, malaria and African sleeping sickness.

Protozoa photo clockwise from top: Giardia intestinalis (causes diarrhea), Trypanosoma brucei (causes sleeping sickness), Plasmodium gametocyte (causes malaria)


Parasite
other micro-organisms break down body tissues or absorb digested food. They can cause infections of internal disorders of the skin which can cause death. Includes a group called parasitic flukes, roundworms and tapeworms, many-celled animals with developed organs. Among the many types, some are parasites - organisms that live in or on another species, usually the damage in the process of host species. Because of their size, parasitic worms grow outside of cells and can reach astronomical size of 30 feet long.

Bugs in the photo, from left to right: Ascaris lumbricoides (intestinal roundworm), Schistosoma mansoni (parasitic worm that lives in contaminated water and causes schistosomiasis or bilharzia)


Fungi
Fungi include yeasts (unicellular), and fungi and molds (multicellular). Unlike plants, fungi do not make their own food. Some species of fungi for their food by breaking down the remains of dead plants and animals. Others are parasites. Examples include fungal infections, fungal infections and athlete's foot.

Mushrooms in the photo, from left to right: Histoplasma capsulatum (histoplasmosis causes lung infection), Penicillium notatum (produces the drug penicillin)

via sdnhm